cEEG Research Articles

Below is a list of research articles showing the benefit of cEEG monitoring for patients in the ICU and EMU.  Links to the full articles have been provided whenever possible.

• Abend NS, Topjian A, Ichord R, et al. Electroencephalographic monitoring during hypothermia after pediatric cardiac arrest. Neurology 2009;72:1931–1940.
• Abend NS, Topjian AA, Gutierrez-Colina AM, et al. Impact of continuous EEG monitoring on clinical management in critically ill children. Neurocrit Care 2011b;15:70–75.
• Aranda A, et al., Generalized convulsive status epilepticus management in adults: a cohort study with evaluation of professional practice. Epilepsia. 2010;51(10):2159–67.
• Bleck, Thomas P., Status Epilepticus and the Use of Continuous EEG Monitoring in the Intensive Care Unit , Continuum Lifelong Learning Neurology 2012;18(3):560–578.
• Chong DJ, Hirsch LJ., Which EEG patterns warrant treatment in the critically ill? Reviewing the evidence for treatment of periodic epileptiform discharges and related patterns. J Clinical Neurophysiology 2005;22:79-91.
• Freeman JM. The use of amplitude-integrated electroencephalography: beware of its unintended consequences. Pediatrics 2007;119:615–617.
• Friedman D, Claassen J, and Hirsch LJ., Continuous Electroencephalogram Monitoring in the Intensive Care Unit Anesth Analg August 2009;109:506-523.
• Glass HC, Glidden D, Jeremy RJ, et al. Clinical neonatal seizures are independently associated with outcome in infants at risk for hypoxic-ischemic brain injury. J Pediatr 2009a;155:318–323.
• Gutierrez-Colina AM, Topjian AA, Dlugos DJ, Abend NS. EEG monitoring in critically Ill children: indications and strategies. Pediatr Neurol 2012;46:158-161.
• Hosain SA, Solomon GE, Kobylarz EJ. Electroencephalographic patterns in unresponsive pediatric patients. Pediatr Neurol 2005;32:162–165.
• Jette N, Claassen J, Emerson RG, Hirsch LJ. Frequency and predictors of nonconvulsive seizures during continuous electroencephalographic monitoring in critically ill children. Arch Neurol 2006;63:1750–1755
• Kilbride RD et. al., How Seizure Detection by Continuous Electrographic Monitoring Affects the Prescribing of Antiepileptic Medications. ArchNeurol. 2009;66(6):723-728
• Mayer SA, et al.,. Refractory status epilepticus: frequency, risk factors, and impact on outcome. Arch Neurol. 2002;59(2):205–10.
• Murray DM, Boylan GB, Ali I, et al. Defining the gap between electrographic seizure burden, clinical expression and staff recognition of neonatal seizures. Arch Dis Child Fetal Neonatal Ed 2008;93:F187–F191
• Oddo M, Carrera E, Claassen J, Mayer SA, Hirsch LJ,, Continuous Electroencephalography in the Medical Intensive Care Unit. Critical Care Med 2009;37:2051-6
• Pisani F, Cerminara C, Fusco C, Sisti L. Neonatal status epilepticus vs recurrent neonatal seizures: clinical findings and outcome. Neurology 2007;69:2177–2185
• Privitera M, Hoffman M, Moore JL, Jester D., EEG detection of nontonic-clonic Status Epilepticus in Patients with Altered Consciousness. Epilepsy Res 1994;18:155-66
• Ronne-Engstrom E, Winkler T. Continuous EEG monitoring in patients with traumatic brain injury reveals a high incidence of epileptiform activity. Acta Neurol Scand 2006;114:47–53
• Rubsamen DS, ed. Mismanagement of Status Epilepticus. Professional Liability Newsletter, CA;1997; 27:3
• Sanchez SM, Carpenter J, Chapman KE, et al. Pediatric ICU EEG monitoring: current Resources and practice in the United states and Canada. J Clin Neurophysiol 2013;30:156–160
• Scher MS, Alvin J, Gaus L, et al. Uncoupling of EEG-clinical neonatal seizures after antiepileptic drug use. Pediatr Neurol 2003;28:277–280.
• Shahwan A, Bailey C, Shekerdemian L, Harvey AS. The prevalence of seizures in comatose children in the pediatric intensive care unit: a prospective video-EEG study. Epilepsia 2010;51:1198–1204
• Silbergleit, Robert, et al, Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus, N Engl J Med 2012;366:591-600
• Towne AR, Pellock JM, Ko D, DeLorenzo RJ. Determinants of mortality in status epilepticus. Epilepsia. 1994;35(1):27–34
• Towne AR, Waterhouse EJ, Boggs, JG, Garnett LK, Brown AJ, Smith, JR, Jr., Delorenzo RJ., Prevalence    of Nonconvulsive Status Epilepticus in Comatose Patients. Neurology 2000;54:340-5
• Williams K, Jarrar R, Buchhalter J. Continuous video-EEG monitoring in pediatric intensive care units. Epilepsia 2011;52:1130–1136
• Vespa PM et. al. Continuous EEG Monitoring in the ICU: Early Findings and Clinical Efficacy. J Clinical Neurophysiology 1999;16(1):1-13
• Wusthof CJ, et. al, Electrographic Seizures During Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy. J Child Neurol. 2011 June ; 26(6): 724–728